Using self-assembled monolayers to model the extracellular matrix
نویسندگان
چکیده
منابع مشابه
Using self-assembled monolayers to model the extracellular matrix.
The extracellular matrix is an insoluble aggregate of large proteins and glycosoaminoglycans that comprises the microenvironment of cells in tissue. The matrix displays a host of ligands that interact with cell-surface receptors to mediate the attachment and spreading of cells and regulate signaling processes. Studies of cell-matrix interactions and downstream signaling processes commonly emplo...
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We review recent developments in the area of self-assembled monolayers (SAMs) and their applications. First, we discuss issues related to the structure, the phase transitions, the phase diagram, and the growth dynamics. We explain how the internal degrees of freedom and the multiple interactions involved can lead to a fairly rich phase behaviour even for systems which are commonly considered ‘s...
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Over the past two decades, self assembled monolayers (SAMs) (Love et al., 2005; Smith et al., 2004; Ulman, 1996) have been extensively studied due to their many applications in various fields such as electrochemistry (Eckerman et al., 2010), biosensors (Nyquist et al., 2000), protein separation (Chun and Stroeve, 2002) and enantiomer separation (Mastai, 2009). SAMs are organic assemblies formed...
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ژورنال
عنوان ژورنال: Acta Biomaterialia
سال: 2009
ISSN: 1742-7061
DOI: 10.1016/j.actbio.2009.01.016